Ischemia

Study findings from Brazil and the United States broaden understanding of ischemia

Published in Blood Weekly, March 8th, 2007

Ischemia is the focus of recent research from Brazil and the United States.

Study 1: Data detailed in "Heme oxygenase 1 and renal ischemia and reperfusion injury: the impact of immunosuppressive drug" have been presented. According to a study from Sao Paulo, Brazil, "Ischemia and reperfusion injury (IRI) is the main etiology of acute renal failure in native and transplanted kidneys. In the transplantation field, immunosuppressive drugs may play an additional role in acute graft dysfunction."

"Acute cyclosporine nephrotoxicity (ATN) can result from vasoconstriction of the afferent arterioles, which may exacerbate deceased renal transplantation. HO-1...

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Source: Blood Weekly (2007-03-08)

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