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Coagulation

Studies from ZLB Behring in the area of coagulation published

Published in Blood Weekly, May 3rd, 2007

New investigation results, "Prothrombin complex concentrate versus recombinant factor VIIa for reversal of coumarin anticoagulation," are detailed in a study published in Thrombosis Research. "Prothrombin complex concentrate (PCC) is recommended for emergency reversal of oral coumarin anticoagulation. Recently, recombinant factor VIIa (rFVIIa) has also been investigated for this purpose, although no direct comparison of PCC and rFVIIa has been reported," scientists writing in the journal Thrombosis Research report.

"This study was designed to compare the effectiveness of PCC and rFVIIa for reversal of both acute and sustained coumarin anticoagulation. In...

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