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Thrombocytopenia Therapy

Study data from Albany College of Pharmacy, College of Pharmacy update understanding of thrombocytopenia therapy

Published in Blood Weekly, May 10th, 2007

Investigators publish new data in the report "Platelet GPIIb/IIIa antagonist, XV459, in heparin-induced thrombocytopenia." According to recent research from the United States, "Heparin-induced thrombocytopenia (HIT) is a serious, immune-related complication of heparin therapy. One of the most severe manifestations of HIT is the development of thromboembolic events, which is based on platelet activation and aggregation caused by HIT-associated antibodies."

"Therapeutic options for patients with HIT are limited despite advancement toward the development of alternative (nonheparin) anticoagulants, such as direct thrombin inhibitors and indirect anti-factor Xa agents....

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