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Anemia

Adverse Event of FG-2216 for the Treatment of Anemia

Published in Blood Weekly, May 24th, 2007

Astellas Pharma Inc. ("Astellas"; headquarters: Tokyo; President and CEO: Masafumi Nogimori) announced that in the phase II clinical trial of FG-2216 (development code. Astellas code name: YM 311) for patients in pre-dialysis chronic kidney disease being conducted in the United States by FibroGen, Inc. ("FibroGen": headquarters: South San Francisco, CA; Chairman, founder and CEO: Thomas B. Neff), there was one case of death by fulminant hepatitis. FG-2216 is a compound for oral anemia treatment for which Astellas has licensed from FibroGen fro exclusive development and marketing in Japan and Europe, etc.

FibroGen has reported this case to the FDA and will be discussing...

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