Liver Transplants
New data from Erasmus University, Department of Surgery illuminate research in liver transplants
Published in Blood Weekly, June 14th, 2007
Research findings, "Allosuppressive donor CD4+CD25+ regulatory T cells detach from the graft and circulate in recipients after liver transplantation," are discussed in a new report. "Organ transplantation (Tx) results in a transfer of donor leukocytes from the graft to the recipient, which can lead to chimerism and may promote tolerance. It remains unclear whether this tolerance involves donor-derived regulatory T cells (Tregs)," scientists in Rotterdam, Netherlands report.
"In this study, we examined the presence and allosuppressive activity of CD4+CD25+Foxp3+ Tregs in perfusates of human liver grafts and monitored the cells presence in the circulation of recipients...
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Source: Blood Weekly (2007-06-14)
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