Ischemia Therapy
Researchers at Zhejiang University, Department of Pharmacology target ischemia therapy
Published in Blood Weekly, July 12th, 2007
Scientists discuss in "Minocycline inhibits 5-lipoxygenase activation and brain inflammation after focal cerebral ischemia in rats" new findings in ischemia. Researchers in Hangzhou, People's Republic of China conducted a study "To determine whether the anti-inflammatory effect of minocycline on postischemic brain injury is mediated by the inhibition of 5-lipoxygenase (5-LOX) expression and enzymatic activation in rats. Focal cerebral ischemia was induced for 30 min with middle cerebral artery occlusion, followed by reperfusion."
"The ischemic injuries, endogenous IgG exudation, the accumulation of neutrophils and macrophage/microglia, and 5-LOX mRNA expression were...
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Source: Blood Weekly (2007-07-12)
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