Leukemia

Recent findings from Research Center for Radiation Emergency Medicine highlight research in leukemia

Published in Blood Weekly, July 12th, 2007

Investigators publish new data in the report "p53 (TRP53) deficiency-mediated antiapoptosis escape after 5 Gy X irradiation still induces stem cell leukemia in C3H/He mice: comparison between whole-body assay and bone marrow transplantation (BMT) assay. Mice exposed to a lethal dose of radiation were repopulated with heterozygous p53(±) (TRP53(±)) bone marrow cells and then exposed to doses of 1, 3 and 5 Gy 1 month later. This resulted in the transplanted bone marrow-specific diseases other than competitively induced nonhematopoietic neoplasms," scientists writing in the journal Radiation Research report.

"Interestingly, the present study showed a...

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Source: Blood Weekly (2007-07-12)

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