Acute Lymphoblastic Leukemia
Researchers from McGill University discuss findings in acute lymphoblastic leukemia in children
Published in Blood Weekly, July 12th, 2007
Data detailed in "Excess transmission of the NAD(P)H:quinone oxidoreductase 1 (NQO1) C609T polymorphism in families of children with acute lymphoblastic leukemia" have been presented. In this recently published study, investigators in Montreal, Canada conducted a study "Topoisomerase II is a DNA-processing enzyme, and secondary acute myeloid leukemia has been associated with exposure to drugs that inhibit its action. Hence, prenatal exposure to chemicals that inhibit topoisomerase II could plausibly contribute to the incidence of childhood leukemia."
"The NAD(P)H:quinone oxidoreductase 1 (NQO1) enzyme is involved in the metabolism of topoisomerase II-inhibiting...
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Source: Blood Weekly (2007-07-12)
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