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Ischemia Cell Biology

Study findings from University of Chicago, Department of Medicine broaden understanding of ischemia cell biology

Published in Blood Weekly, July 26th, 2007

A report, "Altering CO2 during reperfusion of ischemic cardiomyocytes modifies mitochondrial oxidant injury," is newly published data in Critical Care Medicine. "Acute changes in tissue CO2 and pH during reperfusion of the ischemic heart may affect ischemia/reperfusion injury. We tested whether gradual vs. acute decreases in CO2 after cardiomyocyte ischemia affect reperfusion oxidants and injury," scientists in the United States report.

"Comparative laboratory investigation. Institutional laboratory. Embryonic chick cardiomyocytes. Microscope fields of approximately 500 chick cardiomyocytes were monitored throughout 1 hr of simulated...

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