Leukemia Genetics
Investigators at Christian-Albrechts University, Institute of Human Genetics target leukemia genetics
Published in Blood Weekly, August 2nd, 2007
A new study, "A comprehensive genetic and histopathologic analysis identifies two subgroups of B-cell malignancies carrying a t(14;19)(q32;q13) or variant BCL3-translocation," is now available. "The biologic and pathologic features of B-cell malignancies bearing a translocation t(14;19)(q32;q13) leading to a fusion of IGH and BCL3 are still poorly described. Herein we report the results of a comprehensive cytogenetic, fluorescence in situ hybridization (FISH), molecular and histopathological survey of a large series of B-cell malignancies with t(14;19) or variant translocations," scientists writing in the journal Leukemia report.
"A total of 56 B-cell...
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Source: Blood Weekly (2007-08-02)
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