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Vascular Disease

New vascular disease findings from S. Slow and co-authors described

Published in Blood Weekly, August 2nd, 2007

In this recent report, researchers in Christchurch, New Zealand conducted a study "Total plasma homocysteine (Hcy) concentration correlates with risk of vascular disease. Over 80% of chronic renal failure patients have elevated plasma Hey and a 10-20 times higher incidence of vascular disease."

"Glycine betaine lowers plasma Hcy through methylation catalysed by betaine-homocysteine methyltransferase (BHMT). Dimethylthetin (DMT), a synthetic glycine betaine analogue, is a more effective BHMT substrate. DMT is therefore a potential therapeutic agent for reducing plasma Hcy in humans and may be particularly useful in renal failure patients receiving dialysis because of...

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