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Immunology

Scientists at University of Tokyo, Institute of Medical Science publish new data on immunology

Published in Blood Weekly, August 9th, 2007

A report, "Functional analysis of activating receptor LMIR4 as a counterpart of inhibitory receptor LMIR3," is newly published data in Journal of Biological Chemistry. "The leukocyte mono-Ig-like receptor (LMIR) belongs to a new family of paired immunoreceptors. In this study, we analyzed activating receptor LMIR4/CLM-5 as a counterpart of inhibitory receptor LMIR3/CLM-1," scientists in Tokyo, Japan report.

"LMIR4 is expressed in myeloid cells, including granulocytes, macrophages, and mast cells, whereas LMIR3 is more broadly expressed. The association of LMIR4 with Fc receptor-gamma among immunoreceptor tyrosine-based activation motif-bearing molecules was...

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