Thrombosis
Reports summarize thrombosis study results from University of Cambridge, Department of Biochemistry
Published in Blood Weekly, August 16th, 2007
Research findings, "Platelet receptor recognition and cross-talk in collagen-induced activation of platelets," are discussed in a new report. "Comprehensive mapping of protein-binding sites within human collagen III has allowed the recognition motifs for integrin alpha(2)beta(1) and VWF A3 domain to be identified. Glycoprotein VI-binding sites are understood, although less well defined," investigators in Cambridge, the United Kingdom report.
"This information, together with recent developments in understanding collagen fiber architecture, and crystal structures of the receptor collagen-binding domains, allows a coherent model for the interaction of collagen with the...
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Source: Blood Weekly (2007-08-16)
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