Hematopoiesis Genetics
Studies from University of California, Department of Medicine provide new data on hematopoiesis genetics
Published in Blood Weekly, September 6th, 2007
Current study results from the report, "Modeling notch signaling in normal and neoplastic hematopoiesis: global gene expression profiling in response to activated notch expression," have been published. According to a study from the United States, "In normal hematopoiesis, proliferation is tightly linked to differentiation in ways that involve cell-cell interaction with stromal elements in the bone marrow stem cell niche. Numerous in vitro and in vivo studies strongly support a role for Notch signaling in the regulation of stem cell renewal and hematopoiesis."
"Not surprisingly, mutations in the Notch gene have been linked to a number of types of malignancies. To better...
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Source: Blood Weekly (2007-09-06)
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