Sepsis Physiology
Study data from University of Iowa, Department of Internal Medicine provide new insights into sepsis physiology
Published in Blood Weekly, September 13th, 2007
New research, "Impairments in microvascular reactivity are related to organ failure in human sepsis," is the subject of a report. According to a study from the United States, "Severe sepsis is a systemic inflammatory response to infection resulting in acute organ dysfunction. Vascular perfusion abnormalities are implicated in the pathology of organ failure, but studies of microvascular function in human sepsis are limited."
"We hypothesized that impaired microvascular responses to reactive hyperemia lead to impaired oxygen delivery relative to the needs of tissue and that these impairments would be associated with organ failure in sepsis. We studied 24 severe sepsis...
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Source: Blood Weekly (2007-09-13)
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