Leukemia Gene Therapy
New leukemia gene therapy research from Anhui Medical University outlined
Published in Blood Weekly, October 4th, 2007
Investigators publish new data in the report "Down-regulation of EDAG expression by retrovirus-mediated small interfering RNA inhibits the growth and IL-8 production of leukemia cells. Embryonic development associated gene (EDAG), which is overexpressed in hematopoietic neoplasms and leukemia cell lines, has been reported to participate in the leukemia cell differentiation and proliferation. This study investigated whether retrovirus-mediated transfer of a siRNA against EDAG can reduce the growth of leukemia cells which highly express EDAG in vitro and in vivo," scientists in People's Republic of China report.
"The stable transfected cells were identified with RT-PCR,...
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Source: Blood Weekly (2007-10-04)
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