Cord Blood

Reports by S.S. Graves and co-researchers describe recent advances in Cord Blood

Published in Blood Weekly, October 4th, 2007

According to a study from the United States, "Although hematopoietic cell transplantation (HCT) is generally accomplished using a single donor, multiple donors have been used to enhance the speed of engraftment, particularly in the case of umbilical cord blood grafts. Here we posed the question in the canine HCT model whether stable dual-donor chimerism could be established using 2 DLA-identical donors."

"We identified 8 DILA-identical littermate triplets in which the marrow recipients received 2 Gy total body irradiation followed by marrow infusions from 2 donors and postgrafting immunosuppression. All 8 dogs showed initial ''trichimerism,'' which was sustained in 5...

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Source: Blood Weekly (2007-10-04)

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