Chronic Myeloid Leukemia
ChemGenex Announces Second Publication Demonstrating Activity of Ceflatonin(R) in T315I-Positive Chronic Myeloid Leukemia (CML)
Published in Blood Weekly, October 11th, 2007
ChemGenex Pharmaceuticals Limited (ASX:CXS and NASDAQ:CXSP) announced the publication of a clinical communication in Blood (the journal of the American Society of Hematology) demonstrating clinical activity of the company's lead compound, Ceflatonin(R) (Homoharringtonine, HHT(1)) against Gleevec(R) (imatinib mesylate)-resistant, accelerated phase chronic myeloid leukemia (CML) associated with the T315I BCR-ABL kinase domain mutation.
The publication describes positive clinical outcomes for two CML patients with the T315I BCR-ABL kinase domain mutation, one of whom was treated with Ceflatonin, the other was treated with interferon-alpha. The T315I BCR-ABL mutation...
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Source: Blood Weekly (2007-10-11)
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