Biomedicine
New biomedicine research from Cleveland Clinic, Department of Biomedical Engineering discussed
Published in Blood Weekly, October 18th, 2007
Investigators publish new data in the report 'Bone formation following OP-1 implantation is improved by addition of autogenous bone marrow cells in a canine femur defect model.' According to recent research published in the Journal of Orthopaedic Research, "Osteogenic Protein-1 (OP-1, BMP-7) acts locally on connective tissue progenitors (CTPs) to induce bone formation. The response to OP-1 and similar agents is potentially limited by the number of local CTPs."
"This study tested the hypothesis that supplementing local CTPs using autogenous bone marrow will enhance bone formation at an OP-1 implant. Four 1.0-cm diameter unicortical cylindrical defects in the left...
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Source: Blood Weekly (2007-10-18)
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