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Fibrinolysis

Study data from Karolinska University, Department of Hematology update knowledge of fibrinolysis

Published in Blood Weekly, November 8th, 2007

Investigators publish new data in the report 'Laboratory evidence of hyperfibrinolysis in association with low plasminogen activator inhibitor type 1 activity.' "Low activity of plasminogen activator inhibitor type 1 (PAI-1) has been associated with bleeding complications in surgery. We earlier reported a higher prevalence of low PAI-1 activity among patients with bleeding tendency as compared with normal control individuals," investigators in Stockholm, Sweden report.

"The present study evaluated whether low PAI-1 activity actually is associated with markers of increased fibrinolytic activity in plasma from patients with a history of bleeding. PAI-1 activity,...

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