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Endotoxemia

Research results from University of Crete, Medical Department update understanding of endotoxemia

Published in Blood Weekly, November 8th, 2007

"Objectives: Sepsis is a common complication in the early postoperative period, leading to the augmentation of oxidative and nitrosative stresses. The present study investigated the role of enteral nutrition on nitric oxide (NO), production after a lipopolysaccharide (LPS)-induced endotoxemia as an index of nitrosative stress," investigators in Greece report.

"Fifty rats were subjected to midline laparotomy,and feeding gastrostomy. Ten rats served as controls after recovering from operative stress. The remaining rats received, through gastrostomy, enteral nutrition or placebo feeding for 24 h, after which they were injected intraperitoneally with LPS or equal volume of...

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