Leukemia
New findings from Columbia University, Department of Pathology describe advances in leukemia
Published in Blood Weekly, November 22nd, 2007
Current study results from the report, 'Mutational analysis of the N-terminal domain of Moloney murine leukemia virus capsid protein,' have been published. According to a study from the United States, "Retroviral capsid (CA) proteins contain a structurally conserved N-terminal domain (NTD) consisting of a beta-hairpin and six to seven alpha-helices. To examine the role of this domain in Moloney murine leukemia virus (MoMLV) replication, we analyzed 18 insertional mutations in this region."
"All mutants were noninfectious. Based on the results of this analysis and our previous studies on additional mutations in this domain, we were able to divide the NTD of MoMLV CA into...
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Source: Blood Weekly (2007-11-22)
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