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Transplantation

Researchers from University of Dusseldorf describe findings in transplantation

Published in Blood Weekly, November 29th, 2007

According to a study from Dusseldorf, Germany, "Recently, polymorphisms of cytokine genes have been associated with modified gene expression and increased cytokine production. We evaluated the influence of interleukin-10 (IL-10) gene G-1082A, tumour necrosis factor alpha (TNF alpha) gene G-308A and IL-6 gene G-174C polymorphisms on the rejection rate, renal function and long-term outcome in renal transplantation We studied n = 224 consecutive patients, who underwent renal transplantation at our centre from 1998 to 2001 (cadaveric: n = 175, living related: n = 49) followed up for 4.9 +/- 2.0 yr and n = 100 healthy volunteers."

"IL-10 gene G-1082A, TNF alpha gene G-308A...

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