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Recent findings from M. Rokushima and co-authors highlight research in life sciences

Published in Blood Weekly, December 6th, 2007

Fresh data on life sciences are presented in the report 'Toxicogenomics of drug-induced hemolytic anemia by analyzing gene expression profiles in the spleen.' According to recent research from Osaka, Japan, "Hemolytic anemia is a serious adverse effect of therapeutic drugs that is caused by increased destruction of drug-damaged erythrocytes by macrophages in the spleen and liver. We previously applied a toxicogenomic approach to the toxicity by analyzing microarray data of the liver of rats dosed with two hemolytic agents: phenylhydrazine and phenacetin."

"In the present study, we analyzed gene expression profiles in the spleen, the primary organ for destruction of...

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