Sclerosis
Scientists at University of Oxford detail research in sclerosis
Published in Blood Weekly, December 13th, 2007
According to recent research from Oxford, the United Kingdom, "Multiple sclerosis is a disease of the central nervous system that is associated with leukocyte recruitment and subsequent inflammation, demyelination and axonal loss. Endothelial vascular cell adhesion molecule- 1 ( VCAM- 1) and its ligand, alpha(4)beta(1) integrin, are key mediators of leukocyte recruitment, and selective inhibitors that bind to the alpha(4) subunit of alpha(4)beta(1) substantially reduce clinical relapse in multiple sclerosis."
"Urgently needed is a molecular imaging technique to accelerate diagnosis, to quantify disease activity and to guide specific therapy. Here we report in vivo...
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Source: Blood Weekly (2007-12-13)
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