Acute Promyelocytic Leukemia

Research from Nagoya University, Medical Department provide new insights into acute promyelocytic leukemia

Published in Blood Weekly, December 13th, 2007

According to a study from Nagoya, Japan, "Secondary failure of platelet recovery ( SFPR), which is a delayed decline in platelet count after primary recovery following myeloablative hematopoietic SCT, is a significant problem in allogeneic SCT. However, its clinical characteristics have not been well described in autologous SCT for acute myeloid leukemia."

"We reviewed 11 consecutive patients who had received autologous or syngeneic SCT for acute promyelocytic leukemia. Seven of 11 patients (64%) had SFPR, which is defined as a decline in the platelet count to less than 30 000/ mu l for more than 7 days. The median onset of SFPR was day 36 (range, 25-51 days) and the...

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Source: Blood Weekly (2007-12-13)

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