Transplantation

Research results from S. Yang and co-authors update knowledge of transplantation

Published in Blood Weekly, December 20th, 2007

"Myoblast transplantation (MT) is a cell-based gene therapy treatment, representing a potential treatment for Duchenne muscular dystrophy (DMD), cardiac failure and muscle trauma. The rapid and massive death of transplanted cells after MT is considered as a major hurdle which limits the efficacy of MT treatment," scientists writing in the journal Science in China Series C - Life Sciences report.

"Heat shock proteins (HSPs) are overexpressed when cells undergo various insults. HSPs have been described to protect cells in vivo and in vitro against diverse insults. The aim of our study is to investigate whether HSP overexpression could increase myoblast survival...

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Source: Blood Weekly (2007-12-20)

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