Enzyme Research
New research on enzyme research from A.A. Birukova and co-authors summarized
Published in Blood Weekly, December 20th, 2007
According to a study from the United States, "Reorganization of the endothelial cell ( EC) cytoskeleton and cell adhesive complexes provides a structural basis for increased vascular permeability implicated in the pathogenesis of many diseases, including asthma, sepsis, and acute respiratory distress syndrome ( ARDS). We have recently described the barrier- protective effects of hepatocyte growth factor ( HGF) on the human pulmonary EC."
"In the present study, we explored the involvement of Rac- GTPase and Rac- specific nucleotide exchange factor Tiam1 in the mechanisms of EC barrier protection by HGF. HGF protected EC monolayers from thrombin- induced...
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Source: Blood Weekly (2007-12-20)
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