Published in Blood Weekly, December 27th, 2007
"However, transfection efficiencies of (si)RNAs by lipofection tend to be low in primary cells. To address this limitation, we developed an adenoviral vector (AV) driving short hairpin (sh)RNAs against PKCa (Ad-shPKC alpha) and evaluated its potential to silence PKCa in neonatal rat cardiac myocytes and in engineered heart tissues (EHTs), which resemble functional...
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