Ischemia

Research on ischemia published by scientists at University of Bari

Published in Blood Weekly, December 27th, 2007

According to recent research published in the journal Kidney International, "Delayed graft function ( DGF) in kidney transplantation is associated with an increased risk of acute rejection. Myeloid dendritic cells ( DCs) are involved in graft rejection, whereas plasmacytoid DCs may play a role in inducing tolerance."

"We evaluated the presence and phenotype of the DCs in renal graft biopsies of 15 patients with DGF collected before and 7-15 days after transplantation. Biopsies taken from normal patients and from transplant recipients with acute calcineurin inhibitors ( CNIs) nephrotoxicity served as a control group. Specific markers of myeloid, plasmacytoid, and...

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Source: Blood Weekly (2007-12-27)

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