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Cancer Therapy

Data on cancer therapy published by investigators at University College, Conway Institute of Biomolecular and Biomedical Research

Published in Blood Weekly, January 3rd, 2008

Scientists discuss in 'Substituted titanocenes induce caspase-dependent apoptosis in human epidermoid carcinoma cells in vitro and exhibit antitumour activity in vivo' new findings in cancer. According to a study from Ireland, "Titanocene compounds are a novel series of agents that exhibit cytotoxic effects in a variety of human cancer cells in vitro and in vivo. In this study, the antiproliferative activity of two titanocenes (Titanocenes X and Y) was evaluated in human epidermoid cancer cells in vitro."

"Titanocenes X and Y induce apoptotic cell death in epidermoid cancer cells, with IC50 values that are comparable to cisplatin. Characterisation of the...

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