Immunology
Scientists at Weizmann Institute of Science, Department of Immunology target immunology
Published in Blood Weekly, January 10th, 2008
Current study results from the report, 'Tolerance induction in presensitized bone marrow recipients by veto CTLs: effective deletion of host anti-donor memory effector cells,' have been published. "Veto cells have been defined as cells capable of inducing apoptosis of effector CD8 cells recognizing their disparate MHC Ags. Tolerance induced by donor-type veto cells is desirable, because it is restricted to depletion of anti-donor clones without depletion of other immune specificities," scientists in Rehovot, Israel report.
"It has been shown that anti-third party CTLs exhibit marked veto activity with reduced capacity to induce graft-vs-host disease, when tested on...
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Source: Blood Weekly (2008-01-10)
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