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Researchers at Uppsala University, Biomedical Center release new data on life sciences

Published in Blood Weekly, January 10th, 2008

Current study results from the report, 'Identification of dioxygenases required for Aspergillus development. Studies of products, stereochemistry, and the reaction mechanism,' have been published. "Aspergillus sp. contain ppoA, ppoB, and ppoC genes, which code for fatty acid oxygenases with homology to fungal linoleate 7,8-diol synthases (7,8-LDS) and cyclooxygenases. Our objective was to identify these enzymes, as ppo gene replacements show critical developmental aberrancies in sporulation and pathogenicity in the human pathogen Aspergillus fumigatus and the genetic model Aspergillus nidulans," scientists in Uppsala, Sweden report.

"The PpoAs of A....

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