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Hypertension

Research from Medical College of Wisconsin, Medical College reveals new findings on hypertension

Published in Blood Weekly, January 31st, 2008

According to recent research published in the journal Physiological Genomics, "Previous studies have indicated that substitution of chromosome 13 of the salt-resistant Brown Norway BN/SsNHsdMcwi (BN) rat into the genomic background of the Dahl salt-sensitive SS/JrHsdMcwi (SS) rat attenuates the development of salt-sensitive hypertension and renal damage. To identify the regions within chromosome 13 that attenuate the development of hypertension during a high-salt diet in the SS rat, we phenotyped a series of overlapping congenic lines covering chromosome 13, generated from an intercross between the consomic SS-(13BN) rat and the SS rat."

"Blood pressure was...

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