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Bioengineering

Research from University of Wisconsin, Department of Chemistry provides new data on bioengineering

Published in Blood Weekly, January 31st, 2008

Data detailed in 'Modulation of bacterial quorum sensing with synthetic ligands: systematic evaluation of N-acylated homoserine lactones in multiple species and new insights into their mechanisms of action' have been presented. "Bacteria use a language of low molecular weight ligands to assess their population densities in a process called quorum sensing. This chemical signaling process plays a pivotal role both in the pathogenesis of infectious disease and in beneficial symbioses," investigators in the United States report.

"There is intense interest in the development of synthetic ligands that can intercept quorum-sensing signals and attenuate these divergent...

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