Leukemia Therapy
Study findings on leukemia therapy are outlined in reports from Forest Service
Published in Blood Weekly, January 31st, 2008
Research findings, 'Reversal of P-glycoprotein-mediated multidrug resistance by cholesterol derived from low density lipoprotein in a vinblastine-resistant human lymphoblastic leukemia cell line,' are discussed in a new report. According to a study from Edmonton, Canada, "P-glycoprotein (P-gp) is believed to be one of the most common causes of multidrug resistance (MDR) in chemotherapy. Studies have shown that the biosynthesis of cholesterol and cholesterol esters interfere with the function of P-gp."
"Since low density lipoprotein (LDL) carries a large amount of cholesterol, we investigated the effect of cholesterol derived from LDL on a line of human lymphoblastic...
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Source: Blood Weekly (2008-01-31)
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