Life Sciences
Research from Indiana University in the area of life sciences published
Published in Blood Weekly, January 31st, 2008
A report, 'The SLAM-associated protein signaling pathway is required for development of CD4+ T cells selected by homotypic thymocyte interaction,' is newly published data in Immunity. According to a study from the United States, "MHC class II-expressing double-positive thymocytes induce progression of CD4(+) T cell development as efficiently as cortical thymic epithelial cells do. Because double-positive thymocytes expressing CD1d select natural killer T (NKT) cells, we investigated whether thymocyte-selected CD4(+) (T-CD4) T cells require the same signaling components as NKT cells."
"Using bone-marrow chimeras, we found that the signaling molecules SAP, Fyn, and...
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Source: Blood Weekly (2008-01-31)
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