Enzyme Research
Data on enzyme research detailed by researchers at Wyeth
Published in Blood Weekly, February 7th, 2008
New research, 'Involvement of protein kinase Czeta in interleukin-1beta induction of ADAMTS-4 and type 2 nitric oxide synthase via NF-kappaB signaling in primary human osteoarthritic chondrocytes,' is the subject of a report. According to recent research published in the journal Arthritis and Rheumatism, "Protein kinase Czeta (PKCzeta), an atypical PKC, has been found to be transcriptionally up-regulated in human osteoarthritic (OA) articular cartilage. This study was undertaken to examine the role of PKCzeta in interleukin-1beta (IL-1beta)-induced NF-kappaB signaling in human OA chondrocytes, and ultimately to better understand its function in the regulation of downstream mediators...
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Source: Blood Weekly (2008-02-07)
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