Published in Blood Weekly, February 14th, 2008
"In this study, we examined the effects of human proinflammatory cytokines (IL-1 beta, IFN gamma, TNF alpha) on NPI function and cell death. These cytokines have been shown to be cytotoxic to beta cells, in part through the generation of nitric oxide. Therefore, we also examined NPI function after acute oxidative stress caused by streptozotocin (STZ), a nitric oxide-generating beta...
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