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Cleviprex(TM) Demonstrated Rapid, Precise Blood Pressure Control in High-Risk Patients, According to New Analyses

Published in Blood Weekly, February 21st, 2008

The Medicines Company (NASDAQ: MDCO) announced that its investigational agent, Cleviprex(TM) (clevidipine butyrate injectable emulsion), rapidly achieved and maintained blood pressure control in patients with renal dysfunction (RD) and patients with acute heart failure (AHF), according to two new analyses from the Phase III trial VELOCITY(1) presented at the annual meeting of the Society of Clinical Care Medicine (SCCM).

Target blood pressure control was achieved with Cleviprex, administered by intravenous (IV) infusion, by a median of 6.3 minutes for patients with RD and 11.3 minutes for patients with AHF, with 91 percent of RD patients (N=24) and 94 percent of AHF...

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