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Scientists at University of Lleida, Biomedical Research Institute publish research in life sciences

Published in Blood Weekly, March 6th, 2008

Fresh data on life sciences are presented in the report 'Developmental silencing and independency from E2F of apoptotic gene expression in postmitotic tissues.' "The involvement of caspases in postmitotic cell death is controversial. Here we report that adult brain and heart are devoid of many key pro-apoptotic proteins due to a progressive postnatal silencing event involving a reduction of their transcript levels," scientists writing in the journal FEBS Letters report.

"E2F has been shown to control cell cycle progression and to be transcriptional activator of apoptotic genes. However, our data demonstrate that apoptotic gene expression in heart, brain and...

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