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Sepsis

Researchers find possible target to treat deadly bloodstream infections

Published in Blood Weekly, March 13th, 2008

Researchers at the University of Illinois at Chicago have discovered a possible target to treat bloodstream bacterial infections.

Most bacterial pathogens can invade the bloodstream, which can lead to severe sepsis, a syndrome that kills about 215,000 of the 750,000 people affected in the United States each year, according to a study published in the journal Critical Care Medicine.

"The growth of bacterial pathogens in blood represents one of the most dangerous stages of infection," said Alexander Mankin, professor and associate director of UIC's Center for Pharmaceutical Biotechnology. "Before we can discover an antibiotic to treat bloodstream...

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