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Hyperhomocysteinemia

Research conducted at University of Louisville, Medical Department has provided new information about hyperhomocysteinemia

Published in Blood Weekly, March 20th, 2008

According to recent research published in the American Journal of Physiology - Cell Physiology, "Cystathionine-beta-synthase gene transfer and 3- deazaadenosine ameliorate inflammatory response in endothelial cells. Am J Physiol Cell Physiol 293: C1779-C1787, 2007."

"First published September 13, 2007; doi: 10.1152/ajpcell.00207.2007. -Although elevated levels of homocysteine (Hcy) known as hyperhomocysteinemia (HHcy) are associated with increased inflammation and vascular remodeling, the mechanism of Hcy-mediated inflammation and vascular remodeling is unclear. The matrix metalloproteinases (MMPs) and adhesion molecules play an important role in vascular...

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