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Angiotensins

Studies from People's Hospital, Department of Cardiology add new findings in the area of angiotensins

Published in Blood Weekly, March 20th, 2008

Data detailed in 'Intron-2 conversion polymorphism of the aldosterone synthase gene and the antihypertensive response to angiotensin-converting enzyme inhibitors' have been presented. According to recent research from Guangzhou, People's Republic of China, "Aldosterone controls sodium balance and intravascular volume, and thus helps regulate blood pressure. Secretion of aldosterone is mainly regulated at the level of expression of the aldosterone synthase (CYP11B2) gene."

"The intron-2 conversion polymorphism of CYP11B2 was suggested to lead to overexpression of the gene, and may therefore have potential to predict the blood pressure response of patients with essential...

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