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Apoptosis Cell Biology

New apoptosis cell biology research reported from E. Sage and co-authors

Published in Blood Weekly, March 20th, 2008

Research findings, 'Endothelial cell apoptosis in chronically obstructed and reperfused pulmonary artery,' are discussed in a new report. According to recent research from Le Plessis-Robinson, France, "Endothelial dysfunction is a major complication of pulmonary endarterectomy (PTE) that can lead to pulmonary edema and persistent pulmonary hypertension. We hypothesized that endothelial dysfunction is related to increased endothelial-cell (EC) death."

"In piglets, the left pulmonary artery (PA) was ligated to induce lung ischemia then reimplanted into the main PA to reperfuse the lung. Animals sacrificed 5 weeks after ligation (n=5), 2 days after reperfusion (n=5), or 5...

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