Published in Blood Weekly, March 20th, 2008
"A commercial zeta-globin enzyme-linked immunosorbent assay (ELISA) is effective in detecting Southeast Asian (SEA) alpha-thalassemia. We present results of a study of the effectiveness of carrier detection of ELISA and a shortened HbH screen compared with gap polymerase chain reaction. ELISA was superior to the HbH screen for the SEA alpha(0)-thalassemia trait. The ELISA and H screen were equal for detection of all carriers encountered and...
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