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Liver Transplant

A new finding in liver transplantation and antifibrinolytics?

Published in Blood Weekly, March 27th, 2008

Orthotopic liver transplantation (OLT) is associated with severe bleeding and considerable transfusion requirements. There are several reasons for this severe bleeding in OLT. Hemostatic abnormalities remain a major cause.

This study, performed by a team led by Professor Wang Xuehao, is to be published in the March 7, 2008 issue of the World Journal of Gastroenterology.

Aprotinin, a serine protease inhibitor, is used increasingly often in surgeries during operations such as cardiac surgery and liver transplantation to reduce bleeding and transfusion .We performed a meta-analysis to study the effect of aprotinin used in OLT on the intraoperative...

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