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Angiotensins

New findings in angiotensins described by H. Argani and co-researchers

Published in Blood Weekly, April 3rd, 2008

"As renin-angiotensin system (RAS) activity may affect the severity of oxidative stress and inflammatory markers, we assessed the effects of enalapril (E) and/or losartan (L) on these markers in renal transplant recipients with RAS polymorphisms. After determination by PCR of RAS genotypes, consisting of the angiotensin-converting enzymes (ACE I/D), angiotensinogens (AGT M235T) and angiotensin II type 1 receptors (ATR1 A1166C), 76 recipients were recruited randomly and assigned 4 groups," scientists in Iran report.

"The first (n = 17) and second (n = 24) groups were treated with E (E+: 10 mg/d) and L (L+: 50 mg/d) alone, respectively. The third positive control group (n...

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