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Glioblastoma

Research results from University of Tubingen update knowledge of glioblastoma

Published in Blood Weekly, April 10th, 2008

"We have previously reported that bispecific antibodies directed to different target antigens on lymphoma cells and to the death receptor CD95/Fas/Apo-1 selectively kill these cells, thus providing an attractive strategy for the selective stimulation of CD95 on the surface of tumor cells. Here, we further explore the general applicability of this approach under more stringent conditions using various bispecific antibodies directed to different target antigens on glioblastoma cells which express relatively low levels of CD95," scientists writing in the journal Cancer Research report.

"We found that bispecific CD95 antibodies targeting the neuronal glial antigen-2...

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