Lymphocytic Leukemia

Scientists at University of Michigan release new data on lymphocytic leukemia

Published in Blood Weekly, April 10th, 2008

According to a study from the United States, "Chronic lymphocytic leukemia (CLL) is a biologically heterogeneous illness with a variable clinical course."

"Loss of chromosomal material on chromosome 13 at cytoband 13q14 is the most frequent genetic abnormality in CLL, but the molecular aberrations underlying del13q14 in CLL remain incompletely characterized. We analyzed 171 CLL cases for loss of heterozygosity and sulichromosomal copy loss on chromosome 13 in DNA from fluorescence-activated cell sorting-sorted CD19(+) cells and paired buccal cells using the Affymetrix XbaI 50k SNP array platform," wrote P. Ouillette and colleagues, University of Michigan.

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Source: Blood Weekly (2008-04-10)

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